2022 Mercedes-Benz E 350
Problems, Recalls & Reliability Report
Quick Summary
The 2022 Mercedes-Benz E 350 has 9 owner complaints filed with NHTSA — that's 0.9x the segment average of 10. The most common issue is other problems (33% of all complaints), specifically: the panoramic sunroof exploded while inside the car without warning. contacted the dealership/service center on friday 9/15/2023, was told they have not received a memo regarding the panoramic sunroofs in the 2022 e350, however; this is a know problem. i was told that this is not covered of my warra. There are 2 recalls issued for this model year.
9
Total Complaints
2
Recalls Issued
—/5
Safety Stars
0.9x
vs Segment Avg
Known Problems(top 5 of 6)
OTHER
3 complaints- • The panoramic sunroof exploded while inside the car without warning. Contacted the dealership/service center on Friday 9/15/2023, was told they have not received a memo regarding the panoramic sunroofs in the 2022 E350, however; this is a know problem. I was told that this is not covered of my warra
- • My vehicle suddenly stopped in the middle of road. It showed gas tank empty though tank had half tank gas. i would have been hit by a vehicle behind me. Fortunately, there were no vehicles behind me. i filled the remaining half tank , then car started again. I believe that gas sensor was not worki
- • On June 16, 2024, while driving my 2022 Mercedes E 350 with my two young children in the car, my sunroof suddenly and literally exploded. Fortunately, the sunroof screen was closed, which prevented us from sustaining any direct injuries. However, the entire sunroof shattered and is now gone. The ex
“The panoramic sunroof exploded while inside the car without warning. Contacted the dealership/service center on Friday 9/15/2023, was told they have not received a memo regarding the panoramic sunroofs in the 2022 E350, however; this is a know problem. I was told that this is not covered of my warra”
— NHTSA complaint filing
Recalls (2)
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Fuel Cost Calculator for 2022 Mercedes-Benz E 350
Live EIA pricesBased on EPA fuel-economy ratings and EIA weekly retail prices (2026-07-20). Real-world cost varies with driving style, trim/engine, terrain, and traffic.
5-Year Gas Price History
EIA weekly retail data · 2021 → todaySource: US Energy Information Administration weekly retail gasoline prices.
Estimated Insurance Cost for 2022 Mercedes-Benz E 350
How this estimate is calculated
Coverage assumed: 100/300/100 liability + comprehensive/collision, $500 deductibles. Data sources: NAIC 2024 + HLDI loss studies.
Maintenance & Warranty
Recommended Mercedes-Benz E 350 Service Intervals
Service A / Service B alternating schedule. Requires MB-approved oil (229.5 spec typically).
"Severe service" conditions (heavy towing, extreme temps, city stop-and-go) typically halve these intervals. Always consult your vehicle's owner's manual for the authoritative schedule.
Mercedes-Benz New-Vehicle Warranty Coverage
EQ EV battery warranty is 10 years/155,000 miles
These are the terms for a new Mercedes-Benz. If you're buying a used 2022 E 350, remaining coverage is usually pro-rated from the vehicle's original in-service date. Not all coverage transfers between owners — check with a Mercedes-Benz dealer for VIN-specific remaining warranty.
Estimated Repair Costs
Estimates based on average reported repair costs. Actual costs vary by location, shop, and severity.
🔍 Pre-Purchase Inspection Checklist
Based on 9 owner complaints for this specific year, here's what to check or ask about:
- ☐OTHER: The panoramic sunroof exploded while inside the car without warning. Contacted the dealership/service center on Friday 9/15/2023, was told they have not received a memo regarding the panoramic sunroofs in the 2022 E350, however; this is a know problem. I was told that this is not covered of my warra
Typically appears around 50K miles. Repair cost ~$500
- ☐SPEED CONTROL: This vehicle on an ongoing basis is reporting false speed limits. It consistently abruptly drops the indicated speed limit from 70MPH on [XXX] northbound in Salt Lake City. the vehicle slows itself abruptly in traffic that is sometimes dense and traveling 70 to 80. An eventual rear end collision
Typically appears around 50K miles. Repair cost ~$500
- ☐FUEL SYSTEM: The contact owns a 2022 Mercedes-Benz E350. The contact stated that on several occasions while driving at various speeds, the vehicle decelerated while the accelerator pedal was depressed. The contact was able to turn off and restart the vehicle. An unknown warning light was illuminated. The vehicle
Typically appears around 50K miles. Repair cost ~$500
- ☐ELECTRICAL: Auto break suddenly activated during traffic with no obstruction ahead. Also Automatic Headlamp Mode Inoperative comes on and off
Typically appears around 50K miles. Repair cost ~$500
- ☐RECALLS: Verify all 2 recalls have been completed — free at any Mercedes-Benz dealer
- ☐General: Get a pre-purchase inspection from an independent mechanic ($100-$200)
Mercedes-Benz E 350 — Year Comparison
How does 2022 compare to other years? Fewer complaints = more reliable.
Full years-to-avoid analysis →NHTSA Safety Rating
No NHTSA safety rating available
At a Glance
- Complaints
- 9
- Recalls
- 2
- Fire reports
- 0
- Crash reports
- 0
- Injury reports
- 0
- Segment avg
- 10
Check a Specific VIN
See recalls for YOUR 2022 Mercedes-Benz E 350