BestCarRank
Mercedes-Benz

2021 Mercedes-Benz E 450

Problems, Recalls & Reliability Report

Excellent Reliability

Quick Summary

The 2021 Mercedes-Benz E 450 has 8 owner complaints filed with NHTSA — that's 0.1x the segment average of 80. The most common issue is electrical problems (38% of all complaints), specifically: tl* the contact owns a 2021 mercedes-benz e450. the contact stated that while stationary, the instrument panel displayed a message indicating that the vehicle had crashed. after the message was displayed, the vehicle loss motive power. the vehicle was towed to mercedes-benz of fresno (7055 n palm av.

8

Total Complaints

0

Recalls Issued

/5

Safety Stars

0.1x

vs Segment Avg

Known Problems

ELECTRICAL

3 complaints
38%
  • TL* THE CONTACT OWNS A 2021 MERCEDES-BENZ E450. THE CONTACT STATED THAT WHILE STATIONARY, THE INSTRUMENT PANEL DISPLAYED A MESSAGE INDICATING THAT THE VEHICLE HAD CRASHED. AFTER THE MESSAGE WAS DISPLAYED, THE VEHICLE LOSS MOTIVE POWER. THE VEHICLE WAS TOWED TO MERCEDES-BENZ OF FRESNO (7055 N PALM AV
  • I BOUGHT THIS CAR ON 12/12/2021 AND TWO WEEKS AFTER THAT, THE CAR HAD WARNING MESSAGE ON DASHBOARD "COOLANT TOO HOT, STOP THE VEHICLE" ON THE HIGHWAY -NJ TUNPIKE. IT STARTED SLOWING DOWN ON ITS OWN TO BELOW 20MPH, NEARLY KILLED ME WHILE I TRIED TO PULL IT OVER. THEN THE DEALER SERVICE SAID IT HAD DE
  • 48Volt battery failed after three months and just 3,400 miles. I understand this is a recurring problem with Mercedes. Car had to be towed as the vehicle was totally inoperable due to battery malfunction. It took more than three weeks for Mercedes to provide a replacement battery. From what I ha
Typical onset: 50K miles Est. repair: $500

TL* THE CONTACT OWNS A 2021 MERCEDES-BENZ E450. THE CONTACT STATED THAT WHILE STATIONARY, THE INSTRUMENT PANEL DISPLAYED A MESSAGE INDICATING THAT THE VEHICLE HAD CRASHED. AFTER THE MESSAGE WAS DISPLAYED, THE VEHICLE LOSS MOTIVE POWER. THE VEHICLE WAS TOWED TO MERCEDES-BENZ OF FRESNO (7055 N PALM AV

— NHTSA complaint filing

ENGINE

2 complaints
25%
  • I BOUGHT THIS CAR ON 12/12/2021 AND TWO WEEKS AFTER THAT, THE CAR HAD WARNING MESSAGE ON DASHBOARD "COOLANT TOO HOT, STOP THE VEHICLE" ON THE HIGHWAY -NJ TUNPIKE. IT STARTED SLOWING DOWN ON ITS OWN TO BELOW 20MPH, NEARLY KILLED ME WHILE I TRIED TO PULL IT OVER. THEN THE DEALER SERVICE SAID IT HAD DE
  • The 48 volt battery on this mild hybrid vehicle failed and the car was unable to be started on May 3, 2021, with 196 miles on the odometer, a mere 15 days after delivery. It had to be taken by flatbed to the dealer where ultimately the 48 volt battery was replaced. Then again on June 5, 2021, the
Typical onset: 50K miles Est. repair: $500

I BOUGHT THIS CAR ON 12/12/2021 AND TWO WEEKS AFTER THAT, THE CAR HAD WARNING MESSAGE ON DASHBOARD "COOLANT TOO HOT, STOP THE VEHICLE" ON THE HIGHWAY -NJ TUNPIKE. IT STARTED SLOWING DOWN ON ITS OWN TO BELOW 20MPH, NEARLY KILLED ME WHILE I TRIED TO PULL IT OVER. THEN THE DEALER SERVICE SAID IT HAD DE

— NHTSA complaint filing

OTHER

2 complaints
25%
  • The contact owns a 2021 Mercedes-Benz E450. The contact stated that the vehicle speed control was always inadvertently activated, which caused the vehicle to decelerate automatically. The failure nearly caused a collision. The dealer was made aware of the failure and referred the contact to the manu
  • Mercedes Benz issued a recall (Manufacturer Recall Number 2021060021; NHTSA Recall Number 21V354) in May 2021. The recall affects my vehicle's MBUX multimedia system, most importantly, the backup camera, which may fail while in use if this issue is not remedied. I was advised of the recall by them
Typical onset: 50K miles Est. repair: $500

The contact owns a 2021 Mercedes-Benz E450. The contact stated that the vehicle speed control was always inadvertently activated, which caused the vehicle to decelerate automatically. The failure nearly caused a collision. The dealer was made aware of the failure and referred the contact to the manu

— NHTSA complaint filing

WHEELS

1 complaints
13%
  • After the car sits for three or more days, brakes locks up. It takes lots of power to get the brakes to release. It’s a safety concern as the car is parked in the garage with not enough room to maneuver. We never had any car which locks the brakes in this manner. Took it to MB dealer and they say it
Typical onset: 50K miles Est. repair: $500

After the car sits for three or more days, brakes locks up. It takes lots of power to get the brakes to release. It’s a safety concern as the car is parked in the garage with not enough room to maneuver. We never had any car which locks the brakes in this manner. Took it to MB dealer and they say it

— NHTSA complaint filing

Estimated Repair Costs

ELECTRICAL(~50K mi)
$500
ENGINE(~50K mi)
$500
OTHER(~50K mi)
$500
WHEELS(~50K mi)
$500

Estimates based on average reported repair costs. Actual costs vary by location, shop, and severity.

🔍 Pre-Purchase Inspection Checklist

Based on 8 owner complaints for this specific year, here's what to check or ask about:

  • ELECTRICAL: TL* THE CONTACT OWNS A 2021 MERCEDES-BENZ E450. THE CONTACT STATED THAT WHILE STATIONARY, THE INSTRUMENT PANEL DISPLAYED A MESSAGE INDICATING THAT THE VEHICLE HAD CRASHED. AFTER THE MESSAGE WAS DISPLAYED, THE VEHICLE LOSS MOTIVE POWER. THE VEHICLE WAS TOWED TO MERCEDES-BENZ OF FRESNO (7055 N PALM AV

    Typically appears around 50K miles. Repair cost ~$500

  • ENGINE: I BOUGHT THIS CAR ON 12/12/2021 AND TWO WEEKS AFTER THAT, THE CAR HAD WARNING MESSAGE ON DASHBOARD "COOLANT TOO HOT, STOP THE VEHICLE" ON THE HIGHWAY -NJ TUNPIKE. IT STARTED SLOWING DOWN ON ITS OWN TO BELOW 20MPH, NEARLY KILLED ME WHILE I TRIED TO PULL IT OVER. THEN THE DEALER SERVICE SAID IT HAD DE

    Typically appears around 50K miles. Repair cost ~$500

  • OTHER: The contact owns a 2021 Mercedes-Benz E450. The contact stated that the vehicle speed control was always inadvertently activated, which caused the vehicle to decelerate automatically. The failure nearly caused a collision. The dealer was made aware of the failure and referred the contact to the manu

    Typically appears around 50K miles. Repair cost ~$500

  • WHEELS: After the car sits for three or more days, brakes locks up. It takes lots of power to get the brakes to release. It’s a safety concern as the car is parked in the garage with not enough room to maneuver. We never had any car which locks the brakes in this manner. Took it to MB dealer and they say it

    Typically appears around 50K miles. Repair cost ~$500

  • General: Get a pre-purchase inspection from an independent mechanic ($100-$200)

Mercedes-Benz E 450 — Year Comparison

How does 2021 compare to other years? Fewer complaints = more reliable.

Full years-to-avoid analysis →

NHTSA Safety Rating

No NHTSA safety rating available

At a Glance

Complaints
8
Recalls
0
Fire reports
0
Crash reports
0
Injury reports
0
Segment avg
80

Check a Specific VIN

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