2021 Mercedes-Benz E 450
Problems, Recalls & Reliability Report
Quick Summary
The 2021 Mercedes-Benz E 450 has 8 owner complaints filed with NHTSA — that's 0.5x the segment average of 16. The most common issue is electrical problems (38% of all complaints), specifically: tl* the contact owns a 2021 mercedes-benz e450. the contact stated that while stationary, the instrument panel displayed a message indicating that the vehicle had crashed. after the message was displayed, the vehicle loss motive power. the vehicle was towed to mercedes-benz of fresno (7055 n palm av. There are 5 recalls issued for this model year.
8
Total Complaints
5
Recalls Issued
—/5
Safety Stars
0.5x
vs Segment Avg
Known Problems(top 4 of 4)
ELECTRICAL
3 complaints- • TL* THE CONTACT OWNS A 2021 MERCEDES-BENZ E450. THE CONTACT STATED THAT WHILE STATIONARY, THE INSTRUMENT PANEL DISPLAYED A MESSAGE INDICATING THAT THE VEHICLE HAD CRASHED. AFTER THE MESSAGE WAS DISPLAYED, THE VEHICLE LOSS MOTIVE POWER. THE VEHICLE WAS TOWED TO MERCEDES-BENZ OF FRESNO (7055 N PALM AV
- • I BOUGHT THIS CAR ON 12/12/2021 AND TWO WEEKS AFTER THAT, THE CAR HAD WARNING MESSAGE ON DASHBOARD "COOLANT TOO HOT, STOP THE VEHICLE" ON THE HIGHWAY -NJ TUNPIKE. IT STARTED SLOWING DOWN ON ITS OWN TO BELOW 20MPH, NEARLY KILLED ME WHILE I TRIED TO PULL IT OVER. THEN THE DEALER SERVICE SAID IT HAD DE
- • 48Volt battery failed after three months and just 3,400 miles. I understand this is a recurring problem with Mercedes. Car had to be towed as the vehicle was totally inoperable due to battery malfunction. It took more than three weeks for Mercedes to provide a replacement battery. From what I ha
“TL* THE CONTACT OWNS A 2021 MERCEDES-BENZ E450. THE CONTACT STATED THAT WHILE STATIONARY, THE INSTRUMENT PANEL DISPLAYED A MESSAGE INDICATING THAT THE VEHICLE HAD CRASHED. AFTER THE MESSAGE WAS DISPLAYED, THE VEHICLE LOSS MOTIVE POWER. THE VEHICLE WAS TOWED TO MERCEDES-BENZ OF FRESNO (7055 N PALM AV”
— NHTSA complaint filing
Recalls (5)
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.
Estimated Insurance Cost for 2021 Mercedes-Benz E 450
How this estimate is calculated
Coverage assumed: 100/300/100 liability + comprehensive/collision, $500 deductibles. Data sources: NAIC 2024 + HLDI loss studies.
Maintenance & Warranty
Recommended Mercedes-Benz E 450 Service Intervals
Service A / Service B alternating schedule. Requires MB-approved oil (229.5 spec typically).
"Severe service" conditions (heavy towing, extreme temps, city stop-and-go) typically halve these intervals. Always consult your vehicle's owner's manual for the authoritative schedule.
Mercedes-Benz New-Vehicle Warranty Coverage
EQ EV battery warranty is 10 years/155,000 miles
These are the terms for a new Mercedes-Benz. If you're buying a used 2021 E 450, remaining coverage is usually pro-rated from the vehicle's original in-service date. Not all coverage transfers between owners — check with a Mercedes-Benz dealer for VIN-specific remaining warranty.
Estimated Repair Costs
Estimates based on average reported repair costs. Actual costs vary by location, shop, and severity.
🔍 Pre-Purchase Inspection Checklist
Based on 8 owner complaints for this specific year, here's what to check or ask about:
- ☐ELECTRICAL: TL* THE CONTACT OWNS A 2021 MERCEDES-BENZ E450. THE CONTACT STATED THAT WHILE STATIONARY, THE INSTRUMENT PANEL DISPLAYED A MESSAGE INDICATING THAT THE VEHICLE HAD CRASHED. AFTER THE MESSAGE WAS DISPLAYED, THE VEHICLE LOSS MOTIVE POWER. THE VEHICLE WAS TOWED TO MERCEDES-BENZ OF FRESNO (7055 N PALM AV
Typically appears around 50K miles. Repair cost ~$500
- ☐ENGINE: I BOUGHT THIS CAR ON 12/12/2021 AND TWO WEEKS AFTER THAT, THE CAR HAD WARNING MESSAGE ON DASHBOARD "COOLANT TOO HOT, STOP THE VEHICLE" ON THE HIGHWAY -NJ TUNPIKE. IT STARTED SLOWING DOWN ON ITS OWN TO BELOW 20MPH, NEARLY KILLED ME WHILE I TRIED TO PULL IT OVER. THEN THE DEALER SERVICE SAID IT HAD DE
Typically appears around 50K miles. Repair cost ~$500
- ☐OTHER: The contact owns a 2021 Mercedes-Benz E450. The contact stated that the vehicle speed control was always inadvertently activated, which caused the vehicle to decelerate automatically. The failure nearly caused a collision. The dealer was made aware of the failure and referred the contact to the manu
Typically appears around 50K miles. Repair cost ~$500
- ☐WHEELS: After the car sits for three or more days, brakes locks up. It takes lots of power to get the brakes to release. It’s a safety concern as the car is parked in the garage with not enough room to maneuver. We never had any car which locks the brakes in this manner. Took it to MB dealer and they say it
Typically appears around 50K miles. Repair cost ~$500
- ☐RECALLS: Verify all 5 recalls have been completed — free at any Mercedes-Benz dealer
- ☐General: Get a pre-purchase inspection from an independent mechanic ($100-$200)
Mercedes-Benz E 450 — Year Comparison
How does 2021 compare to other years? Fewer complaints = more reliable.
Full years-to-avoid analysis →NHTSA Safety Rating
No NHTSA safety rating available
At a Glance
- Complaints
- 8
- Recalls
- 5
- Fire reports
- 0
- Crash reports
- 0
- Injury reports
- 0
- Segment avg
- 16
Check a Specific VIN
See recalls for YOUR 2021 Mercedes-Benz E 450